Reversal of the Pathophysiological Responses to Gram-Negative Sepsis by Megadose Vitamin C

Oxidative stress appears to initiate organ failure in sepsis, justifying treatment with antioxidants such as vitamin C at megadoses. We have therefore investigated the safety and efficacy of megadose sodium ascorbate in sepsis. DESIGN: Interventional study. SETTING: Research Institute. SUBJECTS: Adu...

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Detalles Bibliográficos
Autores principales: Lankadeva, Yugeesh R., Peiris, Rachel M., Okazaki, Nobuki, Birchall, Ian E., Trask-Marino, Anton, Dornom, Anthony, Vale, Tom A. M., Evans, Roger G., Yanase, Fumitaka, Bellomo, Rinaldo, May, Clive N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Online Laboratory Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803449/
https://www.ncbi.nlm.nih.gov/pubmed/33239507
http://dx.doi.org/10.1097/CCM.0000000000004770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803449/
https://www.ncbi.nlm.nih.gov/pubmed/33239507
http://dx.doi.org/10.1097/CCM.0000000000004770

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