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Site-1 Protease-Derived Soluble (Pro)Renin Receptor Contributes to Angiotensin II–Induced Hypertension in Mice

Activation of PRR ([pro]renin receptor) contributes to enhancement of intrarenal RAS and renal medullary α-ENaC and thus elevated blood pressure during Ang II (angiotensin II) infusion. The goal of the present study was to test whether such action of PRR was mediated by sPRR (soluble PRR), generated...

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Detalles Bibliográficos
Autores principales: Feng, Ye, Peng, Kexin, Luo, Renfei, Wang, Fei, Yang, Tianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803453/
https://www.ncbi.nlm.nih.gov/pubmed/33280408
http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.15100