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L-PGDS deficiency accelerated the development of naturally occurring age-related osteoarthritis

Osteoarthritis (OA) is the most common musculoskeletal disorder among the elderly. It is characterized by progressive cartilage degradation, synovial inflammation, subchondral bone remodeling and pain. Lipocalin prostaglandin D synthase (L-PGDS) is responsible for the biosynthesis of PGD(2), which h...

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Detalles Bibliográficos
Autores principales: Ouhaddi, Yassine, Najar, Mehdi, Paré, Frédéric, Lussier, Bertrand, Urade, Yoshihiro, Benderdour, Mohamed, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne, Fahmi, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803483/
https://www.ncbi.nlm.nih.gov/pubmed/33361529
http://dx.doi.org/10.18632/aging.202367