Cargando…

Apelin protects against ischemia-reperfusion injury in diabetic myocardium via inhibiting apoptosis and oxidative stress through PI3K and p38-MAPK signaling pathways

Among all diabetes mellitus-associated cardiovascular diseases, morbidity of diabetic myocardium with ischemia reperfusion injury (D-IRI) is increasing year by year. We aimed to discover a therapeutic biomarker and investigate its mechanism in D-IRI. High-fat diet and streptozotocin-induced diabetes...

Descripción completa

Detalles Bibliográficos
Autores principales: An, Songtao, Wang, Xi, Shi, Huairui, Zhang, Xueqiang, Meng, Hua, Li, Wenbo, Chen, Dongchang, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803490/
https://www.ncbi.nlm.nih.gov/pubmed/33342766
http://dx.doi.org/10.18632/aging.104106