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Apelin protects against ischemia-reperfusion injury in diabetic myocardium via inhibiting apoptosis and oxidative stress through PI3K and p38-MAPK signaling pathways
Among all diabetes mellitus-associated cardiovascular diseases, morbidity of diabetic myocardium with ischemia reperfusion injury (D-IRI) is increasing year by year. We aimed to discover a therapeutic biomarker and investigate its mechanism in D-IRI. High-fat diet and streptozotocin-induced diabetes...
Autores principales: | An, Songtao, Wang, Xi, Shi, Huairui, Zhang, Xueqiang, Meng, Hua, Li, Wenbo, Chen, Dongchang, Ge, Junbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803490/ https://www.ncbi.nlm.nih.gov/pubmed/33342766 http://dx.doi.org/10.18632/aging.104106 |
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