Biological characteristics of aging in human acute myeloid leukemia cells: the possible importance of aldehyde dehydrogenase, the cytoskeleton and altered transcriptional regulation

Patients with acute myeloid leukemia (AML) have a median age of 65-70 years at diagnosis. Elderly patients have more chemoresistant disease, and this is partly due to decreased frequencies of favorable and increased frequencies of adverse genetic abnormalities. However, aging-dependent differences m...

Descripción completa

Detalles Bibliográficos
Autores principales: Hernandez-Valladares, Maria, Aasebø, Elise, Berven, Frode, Selheim, Frode, Bruserud, Øystein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803495/
https://www.ncbi.nlm.nih.gov/pubmed/33349623
http://dx.doi.org/10.18632/aging.202361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803495/
https://www.ncbi.nlm.nih.gov/pubmed/33349623
http://dx.doi.org/10.18632/aging.202361

Ejemplares similares