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Biological characteristics of aging in human acute myeloid leukemia cells: the possible importance of aldehyde dehydrogenase, the cytoskeleton and altered transcriptional regulation
Patients with acute myeloid leukemia (AML) have a median age of 65-70 years at diagnosis. Elderly patients have more chemoresistant disease, and this is partly due to decreased frequencies of favorable and increased frequencies of adverse genetic abnormalities. However, aging-dependent differences m...
Autores principales: | Hernandez-Valladares, Maria, Aasebø, Elise, Berven, Frode, Selheim, Frode, Bruserud, Øystein |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803495/ https://www.ncbi.nlm.nih.gov/pubmed/33349623 http://dx.doi.org/10.18632/aging.202361 |
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