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Sexual dimorphism in aging hematopoiesis: an earlier decline of hematopoietic stem and progenitor cells in male than female mice

Adult hematopoietic stem and progenitor cells (HSPCs) reside in the bone marrow (BM) ensuring homeostasis of blood production and immune response throughout life. Sex differences in immunocompetence and mortality are well-documented in humans. However, whether HSPCs behave dimorphically between sexe...

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Detalles Bibliográficos
Autores principales: So, Eui-Young, Jeong, Euy-Myoung, Wu, Keith Q., Dubielecka, Patrycja M., Reginato, Anthony M., Quesenberry, Peter J., Liang, Olin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803521/
https://www.ncbi.nlm.nih.gov/pubmed/33378745
http://dx.doi.org/10.18632/aging.202167