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Control of lifespan and survival by Drosophila NF-κB signaling through neuroendocrine cells and neuroblasts

We report a comparative analysis of the effects of immune activation in the fly nervous system using genetic activation models to target Drosophila NF-κB within Toll versus Imd pathways. Genetic gain-of-function models for either pathway pan-neuronally as well as in discrete subsets of neural cells...

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Detalles Bibliográficos
Autores principales: Khor, Sinan, Cai, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803524/
https://www.ncbi.nlm.nih.gov/pubmed/33232282
http://dx.doi.org/10.18632/aging.104196