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Histone methyltransferase SETD2 inhibits tumor growth via suppressing CXCL1-mediated activation of cell cycle in lung adenocarcinoma

The histone H3 lysine 36 methyltransferase SET-domain-containing 2 (SETD2) has been reported to be frequently mutated or deleted in many types of human cancer. However, the role of SETD2 in lung adenocarcinoma (LUAD) has not been well documented. In the present study, we found that SETD2 was signifi...

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Detalles Bibliográficos
Autores principales: Zhou, You, Zheng, Xiao, Xu, Bin, Deng, Haifeng, Chen, Lujun, Jiang, Jingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803529/
https://www.ncbi.nlm.nih.gov/pubmed/33223508
http://dx.doi.org/10.18632/aging.104120