Pentoxifylline enhances antioxidative capability and promotes mitochondrial biogenesis for improving age-related behavioral deficits

Pentoxifylline (PTX) is a non-specific phosphodiesterase inhibitor with pleiotropic effects that is routinely used to treat peripheral vascular disease. In this study, we tested whether PTX could also counteract the detrimental effects of aging in the brain. To accomplish that, we treated aged rats...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Kang, Yunxiao, Qi, Chunxiao, Zhang, Tianyun, Zhao, Hui, Ji, Xiaoming, Yan, Wensheng, Huang, Yuanxiang, Cui, Rui, Zhang, Guoliang, Shi, Geming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803534/
https://www.ncbi.nlm.nih.gov/pubmed/33231568
http://dx.doi.org/10.18632/aging.104155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803534/
https://www.ncbi.nlm.nih.gov/pubmed/33231568
http://dx.doi.org/10.18632/aging.104155

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