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Progesterone receptor isoform-dependent cross-talk between prolactin and fatty acid synthase in breast cancer

Progesterone receptor (PR) isoforms can drive unique phenotypes in luminal breast cancer (BC). Here, we hypothesized that PR-B and PR-A isoforms differentially modify the cross-talk between prolactin and fatty acid synthase (FASN) in BC. We profiled the responsiveness of the FASN gene promoter to pr...

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Detalles Bibliográficos
Autores principales: Menendez, Javier A., Peirce, Susan K., Papadimitropoulou, Adriana, Cuyàs, Elisabet, Steen, Travis Vander, Verdura, Sara, Vellon, Luciano, Chen, Wen Y., Lupu, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803566/
https://www.ncbi.nlm.nih.gov/pubmed/33335078
http://dx.doi.org/10.18632/aging.202289