Cargando…

Progesterone receptor isoform-dependent cross-talk between prolactin and fatty acid synthase in breast cancer

Progesterone receptor (PR) isoforms can drive unique phenotypes in luminal breast cancer (BC). Here, we hypothesized that PR-B and PR-A isoforms differentially modify the cross-talk between prolactin and fatty acid synthase (FASN) in BC. We profiled the responsiveness of the FASN gene promoter to pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Menendez, Javier A., Peirce, Susan K., Papadimitropoulou, Adriana, Cuyàs, Elisabet, Steen, Travis Vander, Verdura, Sara, Vellon, Luciano, Chen, Wen Y., Lupu, Ruth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803566/ https://www.ncbi.nlm.nih.gov/pubmed/33335078 http://dx.doi.org/10.18632/aging.202289

Ejemplares similares

Fatty Acid Synthase Is a Key Enabler for Endocrine Resistance in Heregulin-Overexpressing Luminal B-Like Breast Cancer
por: Menendez, Javier A., et al.
Publicado: (2020)

Fatty Acid Synthase Confers Tamoxifen Resistance to ER+/HER2+ Breast Cancer
por: Menendez, Javier A., et al.
Publicado: (2021)

Heregulin Drives Endocrine Resistance by Altering IL-8 Expression in ER-Positive Breast Cancer
por: Papadimitropoulou, Adriana, et al.
Publicado: (2020)

Binding of the angiogenic/senescence inducer CCN1/CYR61 to integrin α(6)β(1) drives endocrine resistance in breast cancer cells
por: Espinoza, Ingrid, et al.
Publicado: (2022)

Fatty acid synthase (FASN) regulates the mitochondrial priming of cancer cells
por: Schroeder, Barbara, et al.
Publicado: (2021)

The metastasis inducer CCN1 (CYR61) activates the fatty acid synthase (FASN)-driven lipogenic phenotype in breast cancer cells
por: Menendez, Javier A., et al.
Publicado: (2016)

Metabolomic and Mitochondrial Fingerprinting of the Epithelial-to-Mesenchymal Transition (EMT) in Non-Tumorigenic and Tumorigenic Human Breast Cells
por: Cuyàs, Elisabet, et al.
Publicado: (2022)

Tumor Cell-Intrinsic Immunometabolism and Precision Nutrition in Cancer Immunotherapy
por: Cuyàs, Elisabet, et al.
Publicado: (2020)

Metformin as an archetype immuno-metabolic adjuvant for cancer immunotherapy
por: Verdura, Sara, et al.
Publicado: (2019)

Metformin: Targeting the Metabolo-Epigenetic Link in Cancer Biology
por: Cuyàs, Elisabet, et al.
Publicado: (2021)

Nutritional Niches of Cancer Therapy-Induced Senescent Cells
por: Llop-Hernández, Àngela, et al.
Publicado: (2022)

Circulating levels of MOTS-c in patients with breast cancer treated with metformin
por: Cuyàs, Elisabet, et al.
Publicado: (2022)

Fatty acid synthase regulates estrogen receptor-α signaling in breast cancer cells
por: Menendez, J A, et al.
Publicado: (2017)

Tau Phosphorylation in Female Neurodegeneration: Role of Estrogens, Progesterone, and Prolactin
por: Muñoz-Mayorga, Daniel, et al.
Publicado: (2018)

Prolactin Receptor (PRLR) Isoform Expression in the Murine Oviduct
por: Radecki, Kelly C, et al.
Publicado: (2021)

In silico clinical trials for anti-aging therapies
por: Menendez, Javier A., et al.
Publicado: (2019)

Lung Cancer Management with Silibinin: A Historical and Translational Perspective
por: Verdura, Sara, et al.
Publicado: (2021)

Isoform specificity of progesterone receptor antibodies
por: Fabris, Victoria, et al.
Publicado: (2017)

Metabolomic mapping of cancer stem cells for reducing and exploiting tumor heterogeneity
por: Cuyàs, Elisabet, et al.
Publicado: (2017)

Silibinin Suppresses the Hyperlipidemic Effects of the ALK-Tyrosine Kinase Inhibitor Lorlatinib in Hepatic Cells
por: Verdura, Sara, et al.
Publicado: (2022)

Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based “starvation” strategies in BRCA1 carriers
por: Cuyàs, Elisabet, et al.
Publicado: (2016)

Heregulin, a new interactor of the telosome/shelterin complex in human telomeres
por: Menendez, Javier A., et al.
Publicado: (2015)

Progesterone through Progesterone Receptor B Isoform Promotes Rodent Embryonic Oligodendrogenesis
por: González-Orozco, Juan Carlos, et al.
Publicado: (2020)

Genetic polymorphism of prolactin and nitric oxide synthase in Holstein cattle
por: Beishova, Indira Saltanovna, et al.
Publicado: (2023)

Silibinin Overcomes EMT-Driven Lung Cancer Resistance to New-Generation ALK Inhibitors
por: Verdura, Sara, et al.
Publicado: (2022)

Progesterone Receptors in Prostate Cancer: Progesterone receptor B is the isoform associated with disease progression
por: Grindstad, Thea, et al.
Publicado: (2018)

Serum concentrations of progesterone and prolactin as predictors of success in in vitro fertilization: A retrospective cohort study
por: Santander-Pérez, Paulina Alejandra, et al.
Publicado: (2023)

Distribution of estrogen and progesterone receptors isoforms in endometrial cancer
por: Kreizman-Shefer, Hila, et al.
Publicado: (2014)

Short prolactin isoforms are expressed in photoreceptors of canine retinas undergoing retinal degeneration
por: Sudharsan, Raghavi, et al.
Publicado: (2021)

Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity
por: Verdura, Sara, et al.
Publicado: (2020)

Understanding the Inguinal Sinus in Sheep (Ovis aries)—Morphology, Secretion, and Expression of Progesterone, Estrogens, and Prolactin Receptors
por: Alexandre-Pires, Graça, et al.
Publicado: (2017)

Progesterone receptor isoforms A and B: new insights into the mechanism of progesterone resistance for the treatment of endometrial carcinoma
por: Shao, Ruijin
Publicado: (2013)

A conditional mutant of the fatty acid synthase unveils unexpected cross talks in mycobacterial lipid metabolism
por: Cabruja, Matías, et al.
Publicado: (2017)

Modulation of Progesterone Receptor Isoform Expression in Pregnant Human Myometrium
por: Ilicic, Marina, et al.
Publicado: (2017)

Characterization of Nuclear Progesterone Receptor Isoforms in the Term Equine Placenta
por: Nagy, Ahmed M., et al.
Publicado: (2021)

Intraovarian, Isoform-Specific Transcriptional Roles of Progesterone Receptor in Ovulation
por: Smith, Kirsten M., et al.
Publicado: (2022)

Progesterone action in human tissues: regulation by progesterone receptor (PR) isoform expression, nuclear positioning and coregulator expression
por: Scarpin, Katherine M., et al.
Publicado: (2009)

Plasma Prolactin and Progesterone Levels and the Risk of Gestational Diabetes: A Prospective and Longitudinal Study in a Multiracial Cohort
por: Li, Mengying, et al.
Publicado: (2020)

Progesterone, Myo-Inositol, Dopamine and Prolactin Present in Follicular Fluid Have Differential Effects on Sperm Motility Subpopulations
por: Keyser, Shannen, et al.
Publicado: (2021)

The LSD1 inhibitor iadademstat (ORY-1001) targets SOX2-driven breast cancer stem cells: a potential epigenetic therapy in luminal-B and HER2-positive breast cancer subtypes
por: Cuyàs, Elisabet, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_oqpi6pjo0p0hj6fvu6246457o1