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Single cell sequencing reveals cell populations that predict primary resistance to imatinib in chronic myeloid leukemia

The treatment of chronic myeloid leukemia (CML), a disease caused by t(9;22)(q34;q11) reciprocal translocation, has advanced largely through the use of targeted tyrosine kinase inhibitors (TKIs). To identify molecular differences that might distinguish TKI responders from non-responders, we performe...

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Detalles Bibliográficos
Autores principales: Zhang, Weilong, Yang, Beibei, Weng, Linqian, Li, Jiangtao, Bai, Jiefei, Wang, Ting, Wang, Jingwen, Ye, Jin, Jing, Hongmei, Jiao, Yuchen, Chen, Xixi, Liu, Hui, Zeng, Yi-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803567/
https://www.ncbi.nlm.nih.gov/pubmed/33226961
http://dx.doi.org/10.18632/aging.104136