Impairment of Pol β-related DNA base-excision repair leads to ovarian aging in mice

The mechanism underlying the association between age and depletion of the human ovarian follicle reserves remains uncertain. Many identified that impaired DNA polymerase β (Pol β)-mediated DNA base-excision repair (BER) drives to mouse oocyte aging. With aging, DNA lesions accumulate in primordial f...

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Detalles Bibliográficos
Autores principales: Hua, Ke, Wang, Liping, Sun, Junhua, Zhou, Nanhai, Zhang, Yilan, Ji, Feng, Jing, Li, Yang, Yang, Xia, Wen, Hu, Zhigang, Pan, Feiyan, Chen, Xi, Yao, Bing, Guo, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803579/
https://www.ncbi.nlm.nih.gov/pubmed/33223510
http://dx.doi.org/10.18632/aging.104123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803579/
https://www.ncbi.nlm.nih.gov/pubmed/33223510
http://dx.doi.org/10.18632/aging.104123

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