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Inhibition of PAR-1 delays aging via activating AMPK in C. elegans

The antagonistic pleiotropy theory of aging suggests that genes essential for growth and development are likely to modulate aging later in life. Previous studies in C. elegans demonstrate that inhibition of certain developmentally essential genes during adulthood leads to significant lifespan extens...

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Detalles Bibliográficos
Autores principales: Wu, Di, Cai, Waijiao, Zhang, Xuan, Lan, Jianfeng, Zou, Lina, Chen, Samuel J., Wu, Zixing, Chen, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803586/
https://www.ncbi.nlm.nih.gov/pubmed/33232266
http://dx.doi.org/10.18632/aging.104180