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Inhibition of PAR-1 delays aging via activating AMPK in C. elegans
The antagonistic pleiotropy theory of aging suggests that genes essential for growth and development are likely to modulate aging later in life. Previous studies in C. elegans demonstrate that inhibition of certain developmentally essential genes during adulthood leads to significant lifespan extens...
Autores principales: | Wu, Di, Cai, Waijiao, Zhang, Xuan, Lan, Jianfeng, Zou, Lina, Chen, Samuel J., Wu, Zixing, Chen, Di |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803586/ https://www.ncbi.nlm.nih.gov/pubmed/33232266 http://dx.doi.org/10.18632/aging.104180 |
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