Clusterin Protects Lipotoxicity-Induced Apoptosis via Upregulation of Autophagy in Insulin-Secreting Cells

BACKGROUND: There is a great need to discover factors that could protect pancreatic β-cells from apoptosis and thus prevent diabetes mellitus. Clusterin (CLU), a chaperone protein, plays an important role in cell protection in numerous cells and is involved in various cellular mechanisms, including...

Descripción completa

Detalles Bibliográficos
Autores principales: Hong, Seok-Woo, Lee, Jinmi, Kim, Min Jeong, Moon, Sun Joon, Kwon, Hyemi, Park, Se Eun, Rhee, Eun-Jung, Lee, Won-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803614/
https://www.ncbi.nlm.nih.gov/pubmed/33261311
http://dx.doi.org/10.3803/EnM.2020.768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803614/
https://www.ncbi.nlm.nih.gov/pubmed/33261311
http://dx.doi.org/10.3803/EnM.2020.768

Ejemplares similares