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Clusterin Protects Lipotoxicity-Induced Apoptosis via Upregulation of Autophagy in Insulin-Secreting Cells

BACKGROUND: There is a great need to discover factors that could protect pancreatic β-cells from apoptosis and thus prevent diabetes mellitus. Clusterin (CLU), a chaperone protein, plays an important role in cell protection in numerous cells and is involved in various cellular mechanisms, including...

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Detalles Bibliográficos
Autores principales:	Hong, Seok-Woo, Lee, Jinmi, Kim, Min Jeong, Moon, Sun Joon, Kwon, Hyemi, Park, Se Eun, Rhee, Eun-Jung, Lee, Won-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Endocrine Society 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803614/ https://www.ncbi.nlm.nih.gov/pubmed/33261311 http://dx.doi.org/10.3803/EnM.2020.768

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