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The downregulation of IL-18R defines bona fide kidney-resident CD8(+) T cells

Stepwise induction of CD69 and CD103 marks distinct differentiation stages of mucosal Trms. But the majority of non-mucosal Trm lacks CD103 expression. The expression of CD69 alone cannot faithfully define Trm cells in heavily vascularized non-mucosal tissues, such as the kidney. Here, we found that...

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Detalles Bibliográficos
Autores principales: Liao, Wei, Liu, Yong, Ma, Chaoyu, Wang, Liwen, Li, Guo, Mishra, Shruti, Srinivasan, Saranya, Fan, Kenneth Ka-Ho, Wu, Haijing, Li, Qianwen, Zhao, Ming, Liu, Xun, Demel, Erika L., Zhang, Xin, Qiu, Yuanzheng, Lu, Qianjin, Zhang, Nu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803637/
https://www.ncbi.nlm.nih.gov/pubmed/33474536
http://dx.doi.org/10.1016/j.isci.2020.101975