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Metabolomics analysis reveals altered metabolites in lean compared with obese adolescents and additional metabolic shifts associated with hyperinsulinaemia and insulin resistance in obese adolescents: a cross-sectional study

INTRODUCTION: Hyperinsulinaemia and insulin resistance (IR) are strongly associated with obesity and are forerunners of type 2 diabetes. Little is known about metabolic alterations separately associated with obesity, hyperinsulinaemia/IR and impaired glucose tolerance (IGT) in adolescents. OBJECTIVE...

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Detalles Bibliográficos
Autores principales: Müllner, Elisabeth, Röhnisch, Hanna E., von Brömssen, Claudia, Moazzami, Ali A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803706/
https://www.ncbi.nlm.nih.gov/pubmed/33438144
http://dx.doi.org/10.1007/s11306-020-01759-y