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Marek’s disease virus Meq oncoprotein interacts with chicken HDAC 1 and 2 and mediates their degradation via proteasome dependent pathway

Marek’s disease virus (MDV) encodes a basic-leucine zipper (BZIP) protein, Meq, which is considered the major MDV oncoprotein. It has been reported that the oncogenicity of Meq is associated with its interaction with C-terminal binding protein 1 (CtBP), which is also an interaction partner of Epstei...

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Detalles Bibliográficos
Autores principales: Liao, Yifei, Lupiani, Blanca, Izumiya, Yoshihiro, Reddy, Sanjay M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803728/
https://www.ncbi.nlm.nih.gov/pubmed/33437016
http://dx.doi.org/10.1038/s41598-020-80792-2