Carbon nano-onion-mediated dual targeting of P-selectin and P-glycoprotein to overcome cancer drug resistance

The transmembrane P-glycoprotein (P-gp) pumps that efflux drugs are a major mechanism of cancer drug resistance. They are also important in protecting normal tissue cells from poisonous xenobiotics and endogenous metabolites. Here, we report a fucoidan-decorated silica-carbon nano-onion (FSCNO) hybr...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Hai, Liang, Yutong, Yin, Yue, Zhang, Jie, Su, Wen, White, Alisa M., Bin Jiang, Xu, Jiangsheng, Zhang, Yuntian, Stewart, Samantha, Lu, Xiongbin, He, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803730/
https://www.ncbi.nlm.nih.gov/pubmed/33436622
http://dx.doi.org/10.1038/s41467-020-20588-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803730/
https://www.ncbi.nlm.nih.gov/pubmed/33436622
http://dx.doi.org/10.1038/s41467-020-20588-0

Ejemplares similares