Structural basis of GABARAP-mediated GABA(A) receptor trafficking and functions on GABAergic synaptic transmission

GABA(A) receptors (GABA(A)Rs) are the primary fast inhibitory ion channels in the central nervous system. Dysfunction of trafficking and localization of GABA(A)Rs to cell membranes is clinically associated with severe psychiatric disorders in humans. The GABARAP protein is known to support the stabi...

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Detalles Bibliográficos
Autores principales: Ye, Jin, Zou, Guichang, Zhu, Ruichi, Kong, Chao, Miao, Chenjian, Zhang, Mingjie, Li, Jianchao, Xiong, Wei, Wang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803741/
https://www.ncbi.nlm.nih.gov/pubmed/33436612
http://dx.doi.org/10.1038/s41467-020-20624-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803741/
https://www.ncbi.nlm.nih.gov/pubmed/33436612
http://dx.doi.org/10.1038/s41467-020-20624-z

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