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Long non-coding RNA LINC00665 promotes gemcitabine resistance of Cholangiocarcinoma cells via regulating EMT and stemness properties through miR-424-5p/BCL9L axis

Gemcitabine is the first-line chemotherapy drug for cholangiocarcinoma (CCA), but acquired resistance has been frequently observed in CCA patients. To search for potential long noncoding RNAs (lncRNAs) involved in gemcitabine resistance, two gemcitabine resistant CCA cell lines were established and...

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Detalles Bibliográficos
Autores principales: Lu, Min, Qin, Xinglei, Zhou, Yajun, Li, Gang, Liu, Zhaoyang, Geng, Xiwen, Yue, Haodi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803957/
https://www.ncbi.nlm.nih.gov/pubmed/33436545
http://dx.doi.org/10.1038/s41419-020-03346-4