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Immune-tolerance to human iPS-derived neural progenitors xenografted into the immature cerebellum is overridden by species-specific differences in differentiation timing

We xeno-transplanted human neural precursor cells derived from induced pluripotent stem cells into the cerebellum and brainstem of mice and rats during prenatal development or the first postnatal week. The transplants survived and started to differentiate up to 1 month after birth when they were rej...

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Detalles Bibliográficos
Autores principales: Nato, Giulia, Corti, Alessandro, Parmigiani, Elena, Jachetti, Elena, Lecis, Daniele, Colombo, Mario Paolo, Delia, Domenico, Buffo, Annalisa, Magrassi, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803978/
https://www.ncbi.nlm.nih.gov/pubmed/33436685
http://dx.doi.org/10.1038/s41598-020-79502-9