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Immune-tolerance to human iPS-derived neural progenitors xenografted into the immature cerebellum is overridden by species-specific differences in differentiation timing
We xeno-transplanted human neural precursor cells derived from induced pluripotent stem cells into the cerebellum and brainstem of mice and rats during prenatal development or the first postnatal week. The transplants survived and started to differentiate up to 1 month after birth when they were rej...
Autores principales: | Nato, Giulia, Corti, Alessandro, Parmigiani, Elena, Jachetti, Elena, Lecis, Daniele, Colombo, Mario Paolo, Delia, Domenico, Buffo, Annalisa, Magrassi, Lorenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803978/ https://www.ncbi.nlm.nih.gov/pubmed/33436685 http://dx.doi.org/10.1038/s41598-020-79502-9 |
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