Co-stimulation with opposing macrophage polarization cues leads to orthogonal secretion programs in individual cells

Macrophages are innate immune cells that contribute to fighting infections, tissue repair, and maintaining tissue homeostasis. To enable such functional diversity, macrophages resolve potentially conflicting cues in the microenvironment via mechanisms that are unclear. Here, we use single-cell RNA s...

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Detalles Bibliográficos
Autores principales: Muñoz-Rojas, Andrés R., Kelsey, Ilana, Pappalardo, Jenna L., Chen, Meibin, Miller-Jensen, Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804107/
https://www.ncbi.nlm.nih.gov/pubmed/33436596
http://dx.doi.org/10.1038/s41467-020-20540-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804107/
https://www.ncbi.nlm.nih.gov/pubmed/33436596
http://dx.doi.org/10.1038/s41467-020-20540-2

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