Multiplexed characterization of rationally designed promoter architectures deconstructs combinatorial logic for IPTG-inducible systems

A crucial step towards engineering biological systems is the ability to precisely tune the genetic response to environmental stimuli. In the case of Escherichia coli inducible promoters, our incomplete understanding of the relationship between sequence composition and gene expression hinders our abi...

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Detalles Bibliográficos
Autores principales: Yu, Timothy C., Liu, Winnie L., Brinck, Marcia S., Davis, Jessica E., Shek, Jeremy, Bower, Grace, Einav, Tal, Insigne, Kimberly D., Phillips, Rob, Kosuri, Sriram, Urtecho, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804116/
https://www.ncbi.nlm.nih.gov/pubmed/33436562
http://dx.doi.org/10.1038/s41467-020-20094-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804116/
https://www.ncbi.nlm.nih.gov/pubmed/33436562
http://dx.doi.org/10.1038/s41467-020-20094-3

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