A logical network-based drug-screening platform for Alzheimer’s disease representing pathological features of human brain organoids

Developing effective drugs for Alzheimer’s disease (AD), the most common cause of dementia, has been difficult because of complicated pathogenesis. Here, we report an efficient, network-based drug-screening platform developed by integrating mathematical modeling and the pathological features of AD w...

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Detalles Bibliográficos
Autores principales: Park, Jong-Chan, Jang, So-Yeong, Lee, Dongjoon, Lee, Jeongha, Kang, Uiryong, Chang, Hongjun, Kim, Haeng Jun, Han, Sun-Ho, Seo, Jinsoo, Choi, Murim, Lee, Dong Young, Byun, Min Soo, Yi, Dahyun, Cho, Kwang-Hyun, Mook-Jung, Inhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804132/
https://www.ncbi.nlm.nih.gov/pubmed/33436582
http://dx.doi.org/10.1038/s41467-020-20440-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804132/
https://www.ncbi.nlm.nih.gov/pubmed/33436582
http://dx.doi.org/10.1038/s41467-020-20440-5

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