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Improved in vivo imaging method for individual islets across the mouse pancreas reveals a heterogeneous insulin secretion response to glucose

While numerous techniques can be used to measure and analyze insulin secretion in isolated islets in culture, assessments of insulin secretion in vivo are typically indirect and only semiquantitative. The CpepSfGFP reporter mouse line allows the in vivo imaging of insulin secretion from individual i...

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Detalles Bibliográficos
Autores principales: Frikke-Schmidt, Henriette, Arvan, Peter, Seeley, Randy J., Cras-Méneur, Corentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804140/
https://www.ncbi.nlm.nih.gov/pubmed/33436691
http://dx.doi.org/10.1038/s41598-020-79727-8