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SIRT6 promotes angiogenesis and hemorrhage of carotid plaque via regulating HIF-1α and reactive oxygen species

As a member of Sirtuins family, SIRT6 participates in the physiological and pathological progress of DNA repair, anti-aging, metabolism, and so on. Several studies have demonstrated that knockdown of SIRT6 inhibited the development of atherosclerosis (AS), indicated SIRT6 as a protective factor for...

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Detalles Bibliográficos
Autores principales: Yang, Zhou, Huang, Yijun, Zhu, Lei, Yang, Kai, Liang, Kun, Tan, Jinyun, Yu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804142/
https://www.ncbi.nlm.nih.gov/pubmed/33436551
http://dx.doi.org/10.1038/s41419-020-03372-2