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Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes

Genome-wide association studies (GWAS) have discovered numerous genetic variants associated with human behavioural traits. However, behavioural traits are subject to misreports and longitudinal changes (MLC) which can cause biases in GWAS and follow-up analyses. Here, we demonstrate that individuals...

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Detalles Bibliográficos
Autores principales: Xue, Angli, Jiang, Longda, Zhu, Zhihong, Wray, Naomi R., Visscher, Peter M., Zeng, Jian, Yang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804181/
https://www.ncbi.nlm.nih.gov/pubmed/33436567
http://dx.doi.org/10.1038/s41467-020-20237-6