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A selectable, plasmid-based system to generate CRISPR/Cas9 gene edited and knock-in mosquito cell lines
Aedes (Ae.) aegypti and Ae. albopictus mosquitoes transmit arthropod-borne diseases around the globe, causing ~ 700,000 deaths each year. Genetic mutants are valuable tools to interrogate both fundamental vector biology and mosquito host factors important for viral infection. However, very few genet...
Autores principales: | Rozen-Gagnon, Kathryn, Yi, Soon, Jacobson, Eliana, Novack, Sasha, Rice, Charles M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804293/ https://www.ncbi.nlm.nih.gov/pubmed/33436886 http://dx.doi.org/10.1038/s41598-020-80436-5 |
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