Complex of human Melanotransferrin and SC57.32 Fab fragment reveals novel interdomain arrangement with ferric N-lobe and open C-lobe

Melanotransferrin (MTf) is an iron-binding member of the transferrin superfamily that can be membrane-anchored or secreted in serum. On cells, it can mediate transferrin-independent iron uptake and promote proliferation. In serum, it is a transcytotic iron transporter across the blood–brain barrier....

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Detalles Bibliográficos
Autores principales: Hayashi, Kristyn, Longenecker, Kenton L., Liu, Yi-Liang, Faust, Bryan, Prashar, Aditi, Hampl, Johannes, Stoll, Vincent, Vivona, Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804310/
https://www.ncbi.nlm.nih.gov/pubmed/33436675
http://dx.doi.org/10.1038/s41598-020-79090-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804310/
https://www.ncbi.nlm.nih.gov/pubmed/33436675
http://dx.doi.org/10.1038/s41598-020-79090-8

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