Granzyme B inhibition reduces disease severity in autoimmune blistering diseases

Pemphigoid diseases refer to a group of severe autoimmune skin blistering diseases characterized by subepidermal blistering and loss of dermal-epidermal adhesion induced by autoantibody and immune cell infiltrate at the dermal-epidermal junction and upper dermis. Here, we explore the role of the imm...

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Detalles Bibliográficos
Autores principales: Hiroyasu, Sho, Zeglinski, Matthew R., Zhao, Hongyan, Pawluk, Megan A., Turner, Christopher T., Kasprick, Anika, Tateishi, Chiharu, Nishie, Wataru, Burleigh, Angela, Lennox, Peter A., Van Laeken, Nancy, Carr, Nick J., Petersen, Frank, Crawford, Richard I., Shimizu, Hiroshi, Tsuruta, Daisuke, Ludwig, Ralf J., Granville, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804321/
https://www.ncbi.nlm.nih.gov/pubmed/33436591
http://dx.doi.org/10.1038/s41467-020-20604-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804321/
https://www.ncbi.nlm.nih.gov/pubmed/33436591
http://dx.doi.org/10.1038/s41467-020-20604-3

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