Aberrant spinal mechanical loading stress triggers intervertebral disc degeneration by inducing pyroptosis and nerve ingrowth

Aberrant mechanical factor is one of the etiologies of the intervertebral disc (IVD) degeneration (IVDD). However, the exact molecular mechanism of spinal mechanical loading stress-induced IVDD has yet to be elucidated due to a lack of an ideal and stable IVDD animal model. The present study aimed t...

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Detalles Bibliográficos
Autores principales: Fu, Fangda, Bao, Ronghua, Yao, Sai, Zhou, Chengcong, Luo, Huan, Zhang, Zhiguo, Zhang, Huihao, Li, Yan, Yan, Shuxin, Yu, Huan, Du, Weibin, Yang, Yanping, Jin, Hongting, Tong, Peijian, Sun, Zhi-tao, Yue, Ming, Chen, Di, Wu, Chengliang, Ruan, Hongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804398/
https://www.ncbi.nlm.nih.gov/pubmed/33437038
http://dx.doi.org/10.1038/s41598-020-80756-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804398/
https://www.ncbi.nlm.nih.gov/pubmed/33437038
http://dx.doi.org/10.1038/s41598-020-80756-6

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