Autophagy is deregulated in cancer-associated fibroblasts from oral cancer and is stimulated during the induction of fibroblast senescence by TGF-β1

Many of the characteristics ascribed to cancer-associated fibroblasts (CAFs) are shared by activated, autophagic and senescent fibroblasts. Whilst most oral squamous cell carcinomas (OSCCs) are genetically unstable (GU-OSCC), genetically stable variants (GS-OSCC) have been described and, notably, CA...

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Detalles Bibliográficos
Autores principales: Tan, May Leng, Parkinson, E. Kenneth, Yap, Lee Fah, Paterson, Ian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804411/
https://www.ncbi.nlm.nih.gov/pubmed/33436723
http://dx.doi.org/10.1038/s41598-020-79789-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804411/
https://www.ncbi.nlm.nih.gov/pubmed/33436723
http://dx.doi.org/10.1038/s41598-020-79789-8

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