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Gene expression and functional abnormalities in XX/Sry Leydig cells

The SRY gene induces testis development even in XX individuals. However, XX/Sry testes fail to produce mature sperm, due to the absence of Y chromosome carrying genes essential for spermatogenesis. XX/Sry Sertoli cells show abnormalities in the production of lactate and cholesterol required for germ...

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Detalles Bibliográficos
Autores principales: Yanai, Shogo, Baba, Takashi, Inui, Kai, Miyabayashi, Kanako, Han, Soyun, Inoue, Miki, Takahashi, Fumiya, Kanai, Yoshiakira, Ohkawa, Yasuyuki, Choi, Man Ho, Morohashi, Ken-ichirou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804417/
https://www.ncbi.nlm.nih.gov/pubmed/33436964
http://dx.doi.org/10.1038/s41598-020-80741-z