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DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production

Adipose tissue-resident T cells have been recognized as a critical regulator of thermogenesis and energy expenditure, yet the underlying mechanisms remain unclear. Here, we show that high-fat diet (HFD) feeding greatly suppresses the expression of disulfide-bond A oxidoreductase-like protein (DsbA-L...

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Detalles Bibliográficos
Autores principales: Zhou, Haiyan, Peng, Xinyi, Hu, Jie, Wang, Liwen, Luo, Hairong, Zhang, Junyan, Zhang, Yacheng, Li, Guobao, Ji, Yujiao, Zhang, Jingjing, Bai, Juli, Liu, Meilian, Zhou, Zhiguang, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804451/
https://www.ncbi.nlm.nih.gov/pubmed/33436607
http://dx.doi.org/10.1038/s41467-020-20665-4