Sequential dual-drug delivery of BMP-2 and alendronate from hydroxyapatite-collagen scaffolds for enhanced bone regeneration

The clinical use of bioactive molecules in bone regeneration has been known to have side effects, which result from uncontrolled and supraphysiological doses. In this study, we demonstrated the synergistic effect of two bioactive molecules, bone morphogenic protein-2 (BMP-2) and alendronate (ALN), b...

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Detalles Bibliográficos
Autores principales: Lee, Dongtak, Wufuer, Maierdanjiang, Kim, Insu, Choi, Tae Hyun, Kim, Byung Jun, Jung, Hyo Gi, Jeon, Byoungjun, Lee, Gyudo, Jeon, Ok Hee, Chang, Hak, Yoon, Dae Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804460/
https://www.ncbi.nlm.nih.gov/pubmed/33436904
http://dx.doi.org/10.1038/s41598-020-80608-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804460/
https://www.ncbi.nlm.nih.gov/pubmed/33436904
http://dx.doi.org/10.1038/s41598-020-80608-3

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