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Overexpression of neuregulin 1 in GABAergic interneurons results in reversible cortical disinhibition

Cortical disinhibition is a common feature of several neuropsychiatric diseases such as schizophrenia, autism and intellectual disabilities. However, the underlying mechanisms are not fully understood. To mimic increased expression of Nrg1, a schizophrenia susceptibility gene in GABAergic interneuro...

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Detalles Bibliográficos
Autores principales: Wang, Yao-Yi, Zhao, Bing, Wu, Meng-Meng, Zheng, Xiao-Li, Lin, Longnian, Yin, Dong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804852/
https://www.ncbi.nlm.nih.gov/pubmed/33436636
http://dx.doi.org/10.1038/s41467-020-20552-y