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Ultrastructural studies of the neurovascular unit reveal enhanced endothelial transcytosis in hyperglycemia‐enhanced hemorrhagic transformation after stroke

AIMS: Pre‐existing hyperglycemia (HG) aggravates the breakdown of blood–brain barrier (BBB) and increases the risk of hemorrhagic transformation (HT) after acute ischemic stroke in both animal models and patients. To date, HG‐induced ultrastructural changes of brain microvascular endothelial cells (...

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Detalles Bibliográficos
Autores principales: Xu, Xiaomin, Zhu, Liuqi, Xue, Ke, Liu, Jiayi, Wang, Jian, Wang, Guohua, Gu, Jin‐hua, Zhang, Yunfeng, Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804894/
http://dx.doi.org/10.1111/cns.13571