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The AMPAR antagonist perampanel protects the neurovascular unit against traumatic injury via regulating Sirt3

INTRODUCTION: Perampanel is a highly selective and noncompetitive α‐amino‐3 ‐hydroxy‐5‐methyl‐4‐isoxazole propionate receptor (AMPAR) antagonist, which has been used as an orally administered antiepileptic drug in more than 55 countries. Recently, perampanel was shown to exert neuroprotective effect...

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Detalles Bibliográficos
Autores principales: Chen, Tao, Liu, Wen‐Bo, Qian, Xiao, Xie, Ke‐Liang, Wang, Yu‐Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804923/
https://www.ncbi.nlm.nih.gov/pubmed/33421349
http://dx.doi.org/10.1111/cns.13580