The novel Nrf2 activator CDDO‐EA attenuates cerebral ischemic injury by promoting microglia/macrophage polarization toward M2 phenotype in mice

The aim of present study was to explore whether 2‐cyano‐3, 12‐dioxooleana‐1, 9‐dien‐28‐oic acid (CDDO)‐ethylamide (CDDO‐EA) attenuates cerebral ischemic injury and its possible mechanisms using a middle cerebral artery occlusion (MCAO) model in C57BL/6 mice. Our results showed that intraperitoneal i...

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Detalles Bibliográficos
Autores principales: Lei, Xia, Li, Hanxia, Li, Min, Dong, Qiwei, Zhao, Huayang, Zhang, Zongyong, Sun, Baoliang, Mao, Leilei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804925/
https://www.ncbi.nlm.nih.gov/pubmed/33280237
http://dx.doi.org/10.1111/cns.13496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804925/
https://www.ncbi.nlm.nih.gov/pubmed/33280237
http://dx.doi.org/10.1111/cns.13496

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