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The novel Nrf2 activator CDDO‐EA attenuates cerebral ischemic injury by promoting microglia/macrophage polarization toward M2 phenotype in mice
The aim of present study was to explore whether 2‐cyano‐3, 12‐dioxooleana‐1, 9‐dien‐28‐oic acid (CDDO)‐ethylamide (CDDO‐EA) attenuates cerebral ischemic injury and its possible mechanisms using a middle cerebral artery occlusion (MCAO) model in C57BL/6 mice. Our results showed that intraperitoneal i...
Autores principales: | Lei, Xia, Li, Hanxia, Li, Min, Dong, Qiwei, Zhao, Huayang, Zhang, Zongyong, Sun, Baoliang, Mao, Leilei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804925/ https://www.ncbi.nlm.nih.gov/pubmed/33280237 http://dx.doi.org/10.1111/cns.13496 |
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