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Brain cell-derived exosomes in plasma serve as neurodegeneration biomarkers in male cynomolgus monkeys self-administrating oxycodone

BACKGROUND: The United States is currently facing an opioid crisis. Novel tools to better comprehend dynamic molecular changes in the brain associated with the opioid abuse are limited. Recent studies have suggested the usefulness of plasma exosomes in better understanding CNS disorders. However, no...

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Detalles Bibliográficos
Autores principales: Kumar, Ashish, Kim, Susy, Su, Yixin, Sharma, Mitu, Kumar, Pawan, Singh, Sangeeta, Lee, Jingyun, Furdui, Cristina M., Singh, Ravi, Hsu, Fang-Chi, Kim, Jeongchul, Whitlow, Christopher T., Nader, Michael A., Deep, Gagan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804975/
https://www.ncbi.nlm.nih.gov/pubmed/33418508
http://dx.doi.org/10.1016/j.ebiom.2020.103192