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The toxic side of one-carbon metabolism and epigenetics

One-carbon metabolism is a central metabolic hub that provides one-carbon units for essential biosynthetic reactions and for writing epigenetics marks. The leading role in this hub is performed by the one-carbon carrier tetrahydrofolate (THF), which accepts formaldehyde usually from serine generatin...

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Detalles Bibliográficos
Autores principales: Morellato, Agustín E., Umansky, Carla, Pontel, Lucas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804977/
https://www.ncbi.nlm.nih.gov/pubmed/33418141
http://dx.doi.org/10.1016/j.redox.2020.101850