Cynaroside inhibits Leishmania donovani UDP-galactopyranose mutase and induces reactive oxygen species to exert antileishmanial response

Cynaroside, a flavonoid, has been shown to have antibacterial, antifungal and anticancer activities. Here, we evaluated its antileishmanial properties and its mechanism of action through different in silico and in vitro assays. Cynaroside exhibited antileishmanial activity in time- and dose-dependen...

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Detalles Bibliográficos
Autores principales: Tabrez, Shams, Rahman, Fazlur, Ali, Rahat, Alouffi, Abdulaziz S., Akand, Sajjadul Kadir, Alshehri, Bader Mohammed, Alshammari, Fahdah Ayed, Alam, Aftab, Alaidarous, Mohammed A., Banawas, Saeed, Dukhyil, Abdul Aziz Bin, Rub, Abdur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805024/
https://www.ncbi.nlm.nih.gov/pubmed/33367614
http://dx.doi.org/10.1042/BSR20203857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805024/
https://www.ncbi.nlm.nih.gov/pubmed/33367614
http://dx.doi.org/10.1042/BSR20203857

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