Iron overload adversely effects bone marrow haematogenesis via SIRT-SOD2-mROS in a process ameliorated by curcumin

BACKGROUND: Iron overload, which is common in patients with haematological disorders, is known to have a suppressive effect on haematogenesis. However, the mechanism for this effect is still unclear. The antioxidant curcumin has been reported to protect against iron overload-induced bone marrow dama...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Shujuan, Sun, Lan, Qian, Shanhu, Ma, Yongyong, Ma, Ruye, Dong, Yuqing, Shi, Yifen, Jiang, Songfu, Ye, Haige, Shen, Zhijian, Zhang, Shenghui, Shen, Jianping, Yu, Kang, Wang, Siqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805071/
https://www.ncbi.nlm.nih.gov/pubmed/33435886
http://dx.doi.org/10.1186/s11658-020-00244-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805071/
https://www.ncbi.nlm.nih.gov/pubmed/33435886
http://dx.doi.org/10.1186/s11658-020-00244-7

Ejemplares similares